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- Movement disorders
Dr. Michele Hu is Associate Professor at the Nuffield Department of Clinical Neurosciences, University of Oxford and Honorary Consultant Neurologist at Oxford University Hospitals. She obtained her medical degree from King’s College London, completing a PhD in Neuroscience at London University, and her neurology training at the Royal Free, National Hospital London, and Oxford University Hospitals.
Since her appointment as Movement Disorders Neurology Consultant in 2005, she has the advantage of having gained 13 years pragmatic experience looking after Parkinson's and other movement disorders patients, providing a unique insight that can be utilised to full advantage in the delivery of future treatments. She leads the clinical research program on the Oxford Parkinson’s Disease Centre Discovery cohort (OPDC; www.opdc.ox.ac.uk), one of the largest longitudinal cohorts of Parkinson’s patients in the world. Her group facilitates translational research in the field of longitudinal cohort studies and biomarkers for early and prodromal Parkinson’s disease, with particular focus on REM sleep behaviour disorder (RBD), and how sleep affects neurodegeneration.
Areas of interest
Botulinum therapy for dystonia and migraine; Parkinson's disease; Movement disorders, Dystonia, Atypical parkinsonism including PSP, MSA and CBD; General neurology
Current NHS consultant posts held
01/11/05-06/08/13 Neurology Consultant, Milton Keynes Hospital NHS Foundation Trust/ Oxford University Hospitals NHS Trust
07/08/13-Current Associate Professor, Nuffield Department of Clinical Neurosciences, University of Oxford and Consultant Neurologist, Oxford University Hospitals NHS Trust
Michele is co-Principal Investigator of the Oxford Parkinson’s Disease Centre (OPDC), established in 2009 with the £10.7 million Parkinson’s UK-funded Monument Discovery Award to understand the early pathological pathways in Parkinson’s (http://opdc.medsci.ox.ac.uk). Research interests include the use of longitudinal clinical cohorts and brain imaging to develop biomarkers for the early diagnosis/prognostication of Parkinson’s
Gardening, running and spending time with her husband and children outdoors
(Additional) Languages spoken
- German - Basic
Selected recent publications:
1. Arora S, Baig F, Lo C, Barber TA, Lawton MA, Zhan A, Rolinski M, Ruffmann C, Klein JC, Rumbold J, Louvel A, Zaiwalla A, Lennox G, Quinnell T, Dennis G, Wade-Martins R, Ben-Shlomo Y, Little MA, Hu MTM. Smartphone motor testing to distinguish idiopathic REM sleep behavior disorder, controls and PD. Neurology, 2018, DOI 10.1212/WNL.0000000000006366.
2. Barber T, Ludovica G, Muhammed K, Drew D, Bradley K, Crabbe M, Lo C, Mackay C, Husain M, Hu MTM, Klein J. Apathy in rapid eye movement sleep behavior disorder is associated with serotonin depletion in the dorsal raphe nucleus. Brain, 2018, Oct 1;141(10):2848-2854. doi: 10.1093/brain/awy240.
3.Lawton M, Ben-Shlomo Y, May MT, Baig F, Barber TR, Klein, JC, Swallow DMA, Malek N, Grosset KA, Bajaj N, Barker RA, Williams N, Burn DJ, Foltynie T, Morris HR, Wood NW, Grosset DG, Hu MT. Developing and validating Parkinson’s disease subtypes and their motor and cognitive progression. JNNP 2018;0:1-9. doi:10.1136/jnnp-2018-318337.
4. Barber TA, Muhammed K, Drew D, Lawton M, Crabbe M, Rolinski M, Quinnell T, Zaiwalla, Z, Ben-Shlomo Y, Husain M, Hu MT*. Apathy in rapid eye movement sleep behavior disorder is common and under-recognised. Eur J Neurol 2018, Mar;25(3):469-e32. doi: 10.1111/ene.13515. Epub 2017 Dec 14.
5. Barber TR, Lawton M, Rolinski M, Evetts S, Baig F, Ruffmann C, Gornall A, Klein JC, Lo C, Dennis G, Bandmann O, Quinnell T, Zaiwalla Z, Ben-Shlomo Y, Hu MT*. Prodromal Parkinsonism and neurodegenerative risk stratification in REM sleep behaviour disorder. Sleep 2017 Aug 1;40(8).
6. Baig F, Lawton MA, Rolinski M, Ruffmann C, Klein JC, Nithi K, Okai D, Ben-Shlomo Y, Hu MTM*. Personality and addictive behaviours in early Parkinson’s disease and REM sleep behavior disorder. Park Rel Dis. 2017,37:72-28.
7. Michal Rolinski, Ludovica Griffanti, Paola Piccini, Roussakis AA, Szewczyk-Krolikowski K, Menke RA, Quinnell T, Zaiwalla Z, Klein JC, Mackay CE, Hu MT*. Basal ganglia dysfunction in idiopathic REM sleep behaviour disorder parallels that in early Parkinson’s disease. Brain 2016; 139:2224-34.
8. Rolinski MR, Zokaei N, Baig F, Giehl K, Quinnell T, Zaiwalla Z, Mackay CE, Husain M, Hu MTM*. Visual short-term memory deficits in REM sleep behavior disorder mirror those in Parkinson’s disease. Brain 2016, 139:47-53.
Courses offered to GPs
Parkinson's and Movement Disorders Seminars
- MBBS King's College Hospital Medical and Dental School 1993
- MRCP Royal College of Physicians, London 1996
- FRCP Royal College of Physicians, London 2009
- PhD University of London 2001
- CCT Neurology Joint Royal Colleges of Physicians Training Board, London 2005
Reference number 4027225
Professional bodies (positions held - last 3 yrs)
- Fellow Royal College of Physicians, London 2009
- Member Association of British Neurologists 2000
- Member Movement Disorders Society 1997
- Member British Movement Disorders Group 2005
- Member General Medical Council 1993
Details of entry to specialist register
- CCT Neurology, 2005
Affiliations / memberships
- Nuffield Health The Manor Hospital, OX3 7RP
- 09:00 - 13:00
- 01865 231295
Post treatment communication
Following treatment of a Bupa member, I will communicate with GPs in line with Department of Health, GMC and appropriate professional bodies guidelines.
In the event of an urgent query following treatment, Bupa members should use the following contact details
Dr Michele Hu, Consultant Neurologist
0300 304 7777 (via John Radcliffe Switchboard)