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Dr Andrew Duncombe

Haematology

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Overview

Specialises in

  • Haemato-oncology

About me

I achieved first class honours at Oxford University and then studied clinical medicine at St Thomas’. Following general medical training in Oxford and London, i obtained a Wellcome Trust Research Fellowship at the Royal Free Hospital which led to a doctoral thesis at Oxford University. I completed training in haematology through rotations at St Thomas’, St George’s and the Royal Marsden Hospital, London before taking up my current post at University Hospital Southampton in 1994. I have practiced at Spire Southampton since 2001. As lead consultant in clinical haematology from 1995 to 2001.
I have been involved in extensive research into myeloproliferative disorders (disorders of the blood cells). As a core member of the National Cancer Research Institute's myeloproliferative disorders subgroup, I have co-authored national guidelines for the management and treatment of the conditions myelofibrosis and eosinophilia. I have been involved in research with patients with myelofibrosis which has led to the discovery of gene mutations that help to explain why some people are predisposed to acquiring genetic mutations that lead to blood cancers.
I am also highly experienced in lymphoid as well as myeloid blood cancers and involved in clinical trials in these disorders.
I have authored more than 100 original articles and published abstracts including first author publications in the New England Journal of Medicine, Lancet and British Medical Journal. I co-authored the first edition of the Oxford Handbook of Clinical Haematology, and contributed entries on this topic to the British Medical Association Family Health Encyclopedia, which went on to become an international bestseller. While on sabbatical in 2016, i was a visiting guest lecturer at the University of Western Australia, Perth, University of New South Wales, Sydney, University of Otago, NZ and University of Auckland, NZ.
Until my recent retirement from the NHS, I was a National Clinical Excellence Award Holder.

Areas of interest

Myeloproliferative disorders including Polycythaemia, Myelofibrosis, Thrombocythaemia;
Lymphoproliferative disorders including chronic lymphocytic leukaemia; Myelodysplasia; Chronic Myeloid Leukaemia.

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