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I am a general and infectious diseases physician with sub-specialty training in medical mycology (fungal disease). I am a senior clinical lecturer at Imperial College London where I have a particular interest in the interaction between the immune system and infectious diseases. I initially trained in Southampton before undertaking further degrees in infectious diseases at the London School of Hygiene and Tropical Medicine and a PhD at Imperial College London. I lead the fungal diseases unit at the Royal Brompton Hospital.
Areas of interest
I am a general and infectious diseases physician with expertise in all areas of infectious diseases including returning travellers, Lyme disease and chronic infections. I have a particular specialist expertise in infection and immunodeficiency, fungal infections and chronic respiratory infections.
Current NHS consultant posts held
Honorary Consultant Infectious Diseases Physician and Medical Mycologist, Royal Brompton and Harefield NHS Trust
Fungal diseases, chronic respiratory infections, immunodeficiency, novel Immunomodulatory and infection risk
Cycling, running, music, cooking, languages, travel, football
MRC Clinician Scientist
MRC Centenary Award
Marine Biological Laboratory Scholarship
Calcineurin orchestrates lateral transfer of Aspergillus fumigatus during macrophage cell death. Shah A, Kannambath S, Herbst S, Carby M, Reed A, Rogers A, Shaunak S, Armstrong-James D. American Journal of Respiratory and Critical Care Medicine. 2016 Nov 1;194(9):1127-1139.
A subset of virus-specific CD161+ T cells selectively express the multidrug transporter MDR1 and are resistant to chemotherapy in AML. Alsuliman A, Muftuoglu M, Khoder A, Ahn YO, Basar R, Verneris MR, Muranski P, Barrett AJ, Liu E, Li L, Stringaris K, Armstrong-James D, et al. Blood. 2017 Feb 9;129(6):740-758.
Caspofungin Increases Fungal Chitin and Eosinophil and γδ T Cell-Dependent Pathology in Invasive Aspergillosis. Amarsaikhan N, Sands EM, Shah A, Abdolrasouli A, Reed A, Slaven JE, Armstrong-James D, Templeton SP. J Immunol. 2017 Jul 15;199(2):624-632.
Immunotherapeutic approaches to treatment of fungal diseases. Armstrong-James D, Brown GD, Netea MG, Zelante
T, Gresnigt MS, van de Veerdonk FL, Levitz SM. Lancet Infect Dis. 2017 Dec;17(12):e393-e402.
From phagocytosis to metaforosis: Calcineurin's deadly role in innate processing of fungi. Armstrong-James D, de Boer
L, Bercusson A, Shah A. PLoS Pathog. 2018 Jan 4;14(1):e1006627.
- Bachelor of Medicine Southampton University 1996
- Masters in Molecular Infectious Diseases London School of Hygiene and Tropical Medicine 2001
- Doctor of Philosophy Imperial College London 1996
- Diploma in HIV Medicine Society of Apothecaries 2009
- Diploma in Medical Mycology University College London 2014
- Diploma of the London School of Hygeine and Tropical Medicine LSHTM 2002
Reference number 4320351
Affiliations / memberships
Fellow of the Royal College of Physicians
Post treatment communication
Following treatment of a Bupa member, I will communicate with GPs in line with Department of Health, GMC and appropriate professional bodies guidelines.