Current NHS consultant posts held
Consultant Neurologist,
Milton Keynes and Oxford
Research interests
Epilepsy,
Autism
Personal interests
Tennis,
Piano,
Chess
Awards received
Wellcome Trust Research Training Fellowship,
MRC Clinician-Scientist Fellowship,
Simon's Foundation Investigator Award
Languages spoken
English
Publications
Jacob J*, et al. Valproic Acid silencing of ascl1b/ascl1 results in the failure of serotonergic differentiation in a zebrafish model of Fetal Valproate Syndrome.
Dis Model Mech. 2013 Oct 17. PMID: 24135485
John Jacob*, et al “A chemical-genetics approach to study the molecular pathology of central serotonin abnormalities in fetal valproate syndrome”
Lancet Feb 2013, S55.
Jacob J*, et al “Distinct neuronal identities specified by quantitative differences in the transcription factor, Ascl1”
Current Biology 2013 Mar 4; 23(5):412-8 2013 PMID: 23416099
Jacob J*, et al “Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the hindbrain”
Development 2009 136(14): 2477-85
Jacob J*, et al “Temporal control of neural diversity: common regulatory principles in insects and vertebrates?”
Development 2008; 135(21): 3481-9
Jacob J, et al. “Transcriptional cross-repression coordinates the temporal switch from motor to serotonergic neurogenesis in the hindbrain”
Nat Neurosci, 2007; Nov; 10(11):1433-9 (Paper flagged by Faculty of 1000)
Hilton DA, Jacob J, et al. Complications following sural and peroneal nerve biopsies”
JNNP 2007; Jun 5
Jacob J and Briscoe J “Gli proteins and the control of spinal cord patterning”
EMBO Reports 2003; 4(8): 761-5
Jacob J, et al “The clinico-pathological spectrum of Rosenthal Fibre Encephalopathy and Alexander’s disease: a case report and review of the literature”
JNNP, 2003; 74(6): 807-10
Joseph FG, Jacob J and Carrington D “SSPE – a forgotten disease?”
European Journal of Neurology 2002; 9(5): 541-5
Jacob J, et al “Molecules and mechanisms in motor neuron specification and axon pathfinding”
Bioessays 2001; 23:582-595
Jacob J, et al “Role of the target in the pathfinding of facial visceral motor axons”
MCN 2000; 16(1): 14-26
Jacob J, Guthrie S “Facial visceral motor neurons display specific rhombomere origin and axon pathfinding behaviour in the chick”
J Neurosci 2000; 20(20): 7664-71
Courses offered to GPs
Epilepsy,
General Neurology
