Current NHS consultant posts held
Consultant Neurologist and Neuro-oncologist at the National Hospital for Neurology and Neurosurgery
Consultant Neurologist at the North Middlesex Hospital
Research interests
Dr Hotton current research interests are in the imaging and optimisation of the medical management of patients with central nervous system tumors.
Awards received
2006 William Koller Award for innovative research (Movement Disorder Society)
Publications
Original Articles
Gill S, Patel N, Hotton G, O’Sullivan K, McCarter R, Bunnage M, Brooks D, Svendson C, Heywood P. Direct Infusion of glial cell line derived neurotrophic factor (GDNF) in Parkinson’s Disease. Nat Med. 2003:9:589-595.
Love S, Plaha P, Patel NK, Hotton GR, Brooks DJ, Gill SS. Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain. Nat Med 2005;11:703-704.
Gerhard A, Pavese A, Hotton G, Turkheimer F, Es M, Hammers A, Eggert K, Oertel W, Banati RB, Brooks DJ. In vivo imaging of microglial activation with [11C] (R) -PK11195 PET in idiopathic Parkinson’s disease. Neurobiology of Disease 2006; 21: 404-12.
Edison P, Archer H, Hinz R, Hammers A, Pavese N, Tai Y, Hotton G, Fox N, Kennedy A, Rossor M, Brooks DJ. Amyloid deposition and metabolic dysfunction in Alzheimer’s disease and mild cognitive impairment: An 11C-PIB and 18F-FDG PET study. Neurology 2007; 68: 501-8.
Thobois S, Hotton G, Pinto S, Wilkinson L, Limousin-Dowsey P, Brooks DJ, Jahanshahi M. In Parkinson’s disease, subthalamic nucleus stimulation alters pallidal coupling with prefrontal, cingulate, and temporal cortices during random number generation. JCBFM 2007; 27: 1173-84.
Sawamoto N, Piccini P, Hotton G, Pavese N Thielmans K, Brooks DJ. Cognitive deficits and striato-frontal dopamine release in Parkinson’s disease. Brain. 2008;131:1294-1302.
Book Chapters
Hotton G and Clough C. Other Drug Related Movement Disorders in Drug Related Movement Disorders ed. K. Sethi. Marcel Decker 2004
Reviews
Hotton G. Anti-epileptic treatment for patients with brain tumors and epilepsy . Key Opinions in Medicine.
Web Pages / Web based leaning tools
Hotton G and Chauhuri R. Parkinson’s Disease. www.netdoctor.co.uk
Hotton G. Management of Patients with CNS Tumors. www.ebrainjnc.com
