- Fee assured
- Awaiting verification
- Coronary angiography
- Fractional flow reserve (FFR)
- Interventional cardiology
- Percutaneous coronary intervention with/without stenting
- Reporting of echocardiography
I qualified from Guy's and St Thomas' Hospitals Medical School in 1996 graduating with University Honours. I underwent post-graduate training at Hammersmith, Royal Brompton and King's College Hospitals in London and undertook a two year interventional cardiology fellowship at the Aalst Cardiovascular Centre in Belgium. I was appointed as Clinical Lecturer in Cardiology at King's College London in 2008 prior to taking up my current post as Consultant Cardiologist at King's College Hospital in 2010.
I have received over 11 awards, scholarships and prizes including the British Cardiac Society John Parker Fellowship (2005-2007) and Golding Bird and Treasures Medals.
In 2012 I was invited to join a panel of 5 cardiologists to provide a comprehensive round-the-clock cardiology opinion for the Olympic Family during the 2012 London Olympic Games.
Areas of interest
coronary artery disease; chest pain; angina; breathlessness; myocardial infarction; heart attack; hypertension; high blood pressure, high cholesterol; cardiac risk factors; palpitations; atrial fibrillation; pericarditis; heart failure; cardiomyopathy; dilated cardiomyopathy; hypertrophic cardiomyopathy; restrictive cardiomyopathy; myocarditis; stroke; TIA; heart valve disease; aortic valve stenosis; aortic valve regurgitation; bicuspid aortic valve; mitral valve regurgitation; mitral valve prolapse; mitral valve stenosis; tricuspid valve disease; coronary angiography; coronary angioplasty; stenting; radial coronary angiography; primary angioplasty; fractional flow reserve; FFR; intravascular ultrasound; IVUS; optical coherence tomography; OCT; patent foramen ovale; PFO; closure of PFO; atrial septal defect; ASD; closure of ASD; left atrial appendage; LAA; closure of LAA; cardioversion; echocardiography; ECG; 24-hour blood pressure monitoring; 24-hour ECG monitoring; stress test
Current NHS consultant posts held
Ongoing clinical research programme with emphasis on applied coronary physiology and all aspects of interventional cardiology, in particular myocardial infarction. Involved in multiple international clinical trials. To date I have co-supervised two students at King's College London.
My work is supported through a number of scientific grants and over the past five years I have received awards from the British Cardiac Society, British Heart Foundation and National Academy of Sciences.
Throughout my career I have received over 11 Awards, Scholarships, Prizes and Medals in cardiology as well as medicine including the prestigious British Cardiac Society John Parker Fellowship (2005-2007), the Ford Caiger Prize in Cardiology, the Golding Bird Medal in Molecular Biology and the Treasurers' Medal of Guy’s and St Thomas’ Hospitals.
Melikian N, Kearney MT, Thomas MR, et al. A simple thermodilution technique to assess coronary endothelium-dependent microvascular function in humans: Validation and comparison with coronary flow reserve. Eur Heart J 2007; 28: 88-94.
Melikian N, Chowienczyk P, MacCarthy PA, et al. The association between endothelial function and systemic inflammation in asymptomatic subjects with without the metabolic syndrome. Atherosclerosis 2008; 197: 375-382.
Cuisset T, Hamilos M, Melikian N, et al. Direct stenting for stable angina pectoris is associated with reduced periprocedural microcirculatory injury compared with pre-dilation. J Am Coll Cardiol 2008; 51: 1060-1065.
Melikian N, Wijns W. Drug eluting stents: a critique. Heart 2008; 94: 145-152.
Seddon M, Melikian N, Dworakowski et al. Effects of neuronal nitric oxide synthase on human coronary artery diameter and blood flow in vivo. Circulation 2009; 119: 2656-2662.
Melikian N, De Bondt P, Cuisset T, et al. Fractional flow reserve (FFR) and MIBI SPECT: A comparison in patients with multi-vessel coronary artery disease. JACC Cardiovasc Interv 2010; 3: 307-314.
Melikian N, Vercauteren S, Fearon WF, et al. The influence of coronary atherosclerosis on the index of microcirculatory resistance (IMR). EuroIntervention 2010; 5: 939-945.
Shabeeh H, Melikian N, Dworakowski R et al. Differential role of endothelial versus neuronal nitric oxide synthase in the regulation of coronary blood flow during pacing-induced increase in cardiac workload. Am J Physiol Heart Circ Physiol 2013; 304: H1277-1282.
Scott P, Sirker A, Dworakowski R, Paul G, Candilio L, Jahagridar N, Melikian N, Byrne J. FFR in the transradial era: Will hand vein adenosine suffice? A comparative study of the extent, rapidity, and stability of hyperemia from hand and femoral venous routes of adenosine administration. JACC Cardiovasc Interv 2015; 20: 527-535.
Shabeeh H, Khan S, Jiang B, Brett S, Melikian N, Vasadei B, Chowienczyck PJ, Shah AM. Blood pressure is healthy humans is regulated by neuronal NO synthase. Hypertension 2017; 69: 970-976.
- BSc (Hons) Guy's and St Thomas' Hospitals Medical School, University of London 1993
- MBBS (Hons) Guy's and St Thomas' Hospitals Medical School, University of London 1996
- MD King's College London School of Medicine, University of London 2009
Reference number 4323567
Professional bodies (positions held - last 3 yrs)
- MRCP (UK) Royal College of Physicians of London 1999
- FRCP (UK) Royal College of Physicians of London 2014
Affiliations / memberships
Royal College of Physicians, British Cardiac Intervention Society, British Medical Association
Post treatment communication
Following treatment of a Bupa member, I will communicate with GPs in line with Department of Health, GMC and appropriate professional bodies guidelines.
In the event of an urgent query following treatment, Bupa members should use the following contact details
Dr N Melikian
24/7 emergency contact line: 07766 954292