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Consultant Haematologist – Visiting Professor of Biomedical Science, University of Lincoln
I am currently running 4 clinics: 2 general hematology clinic (Myeloma, Leukemia, LPD/CLL, MDS), 1 lymphoma clinic, 1 MPD clinic for an average number of 130 patients per week. I am responsible for the Hematology Ward in Boston and Lincoln. I am participating in on call on a 1:4 based rota. Member of Leukemia, Myeloma, CLL, Lymphoma MDTs.
Fully qualified for hematology lab activity (BM and PB reports, Transfusion issues etc.)
I am responsible for teaching medical students and junior doctors.
I am responsible for a molecular biology lab in Lincoln University.
Areas of interest
• Haematology malignancies • Myeloproliferative disorders • Acute leukemia • Lymphoma • Multiple myeloma
Current NHS consultant posts held
Clinical Director Clinical Support Services
Haematology EGAC Lead East Midland
Visiting Professor of Biomedical Science, University of Lincoln
Alternative pathways in MPN
GATA1 expression in MDS
Preferential nuclear accumulation of JAK2V617F in CD34+ but not in granulocytic, megakaryocytic or erythroid cells of patients with Philadelphia-negative myeloproliferative neoplasia.
Rinaldi CR, et alBlood. 2010 Dec 23;116(26)
JAK2V617F mutation persists in blasts and mature cells of transformed-JAK2V617F-positive-myeloproliferative neoplasia: A European Leukemia Net (ENL) study. Ciro R. Rinaldi, et al. The American Journal of Hematology. Accepted Article Online: Feb 16 2010.
EVI1 Impairs myelopoiesis by deregulation of PU.1 function.
Laricchia-Robbio L, Premanand K, Rinaldi CR, Nucifora G.
Cancer Res. 2009 Feb 15;69(4):1633-42.
Consistent up-regulation of Stat3 Independently of Jak2 mutations in a new murine model of essential thrombocythemia.
Senyuk V, Rinaldi CR, et al. Cancer Res. 2009 Jan 1;69(1):262-71
Sequential continuous infusion of fludarabine and cytarabine associated with liposomal daunorubicin (DaunoXome) (FLAD) in primary refractory or relapsed adult acute myeloid leukemia patients.
Camera A, Rinaldi CR, et al.Ann Hematol. 2009 Feb;88(2):151-8. Epub 2008 Aug 16.
GATA1 is overexpressed in patients with essential thrombocythemia and polycythemia vera but not in patients with primary myelofibrosis or chronic myelogenous leukemia.
Rinaldi CR, et al. Leuk Lymphoma. 2008 Jul;49(7):1416-9.
Repression of RUNX1 activity by EVI1: a new role of EVI1 in leukemogenesis.
Senyuk V, Sinha KK, Li D, Rinaldi CR, et al. Cancer Res. 2007 Jun 15;67(12):5658-66.
RUNX1-RUNX1 homodimerization modulates RUNX1 activity and function.
Li D, Sinha KK, Hay MA, Rinaldi CR, et al. J Biol Chem. 2007 May 4;282(18):13542-51.
Point mutations in two EVI1 Zn fingers abolish EVI1-GATA1 interaction and allow erythroid differentiation of murine bone marrow cells.
Laricchia-Robbio L, Fazzina R, Li D, Rinaldi CR, et al. Mol Cell Biol. 2006 Oct;26(20):7658-66.
Regulation of normal and malignant megakaryopoiesis.
Rinaldi CR, et al. Recent Progress in Cancer Research, 2007 – ISBN 81-7895-253-X –Charter 10– p173 REVIEW
Molecular Mechanisms in Philadelphia Negative Myeloproliferative Neoplasia
By Ciro Roberto Rinaldi, et al.Hematology - Science and Practice,
Courses offered to GPs
Professional Society Memberships:
1. Italian Society of Hematology (SIE)
2. Italian Society of Experimental Hematology (SIES)
3. European Hematology Association (EHA)
4. American Society of Hematology (ASH)
5. European Leukemia Net (ENL)
6. Italian ET Registry (RIT)
7. MPN GIMEMA Working Party
8. NCRI MPN
- Medical Degree University Federico II Naples Italy 2003
- Haematology University Federico II Naples Italy 2007
- PhD Biotechnology University Federico II Naples Italy 2010
Reference number 7081029
Details of entry to specialist register
- GMC Full registration and registered in specialist register , 2010
- The Bostonian, PE21 9QS
- 17:00 - 19:00
- 07788 714030
Post treatment communication
Following treatment of a Bupa member, I will communicate with GPs in line with Department of Health, GMC and appropriate professional bodies guidelines.
Other ways of contacting me
I can be contacted directly using Skype. My Skype ID is: tamaciro