Dr Mark Tremelling: Gastroenterology , General (internal) medicine

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Dr Mark Tremelling

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Overview

Specialises in

Endoscopy

Inflammatory bowel disease

About me

Dr. Tremelling qualified in 1997 and trained as a gastroenterologist in the Eastern Region with specialist training and a research period at Addenbrookes Hospital Cambridge. He was appointed as consultant gastroenterologist at the Norfolk and Norwich University Hospital in 2010. He has served as clinical director for gastroenterology and is currently clinical lead for inflammatory bowel diseases.
Dr. Tremellings particular interests are treatment of inflammatory bowel disease, irritable bowel syndrome and interventional colonoscopy.
Dr. Tremelling has a large NHS practice of patients with both general gastroenterology problems and inflammatory bowel diseases.

Areas of interest

Bowel disease including inflammatory (IBD); Crohn's disease; Ulcerative colitis; Endoscopic procedures; Colonoscopy; Gastroscopy; Interventional endoscopy; Irritable bowel syndrome (IBS); coeliac disease; bowel cancer

Medical secretaries

Sonia Colbert
Hill House Consulting Rooms Spire Norwich Hospital Watton Road NORWICH NR4 7TD
01603 868326
01603 868326
soniacolbert1@gmail.com

About me

External resources

NHS Web page

Current NHS consultant posts held

Consultant Gastroenterologist at Norfolk and Norwich University Hospital.
Clinical Lead for inflammatory bowel diseases
Accredited bowel cancer screening programme colonoscopist

Research interests

Dr. Tremelling's research aims to understand the molecular basis of inflammator bowel diseases (Ulcerative colitis and Crohn's disease). Previous work has identified numerous genes which increase susceptibility to these conditions. Current work along with researchers at the University of East Anglia and Institute for Food Research aims to identify how these genes influence susceptibility.
Dr. Tremelling is also actively involved in clinical trials of new therapies for these conditions.

Personal interests

Dr. Tremelling has four children. He is an enthusiastic road cyclist.

Publications

Dr. Tremelling's research highlights include:

1. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Jostins et al. Nature. 2012 Nov 1;491(7422):119-24

2. Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship. Anderson et al. Gastroenterology. 2009 Feb;136(2):523-9

3. Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Fisher SA, Tremelling M et al. Nat Genet. 2008 Jun;40(6):710-2

4. IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease. Tremelling M et al. Gastroenterology 2007 May;132(5):1657-64

5. Complex insertion/deletion polymorphism in NOD1 (CARD4) is not associated with inflammatory bowel disease susceptibility in East Anglia panel.

Tremelling M, et al. Inflamm Bowel Dis. 2006 Oct;12(10):967-71

Courses offered to GPs

Recent talks to GPs include the use of calprotectin in screening for inflammatory bowel diseases; management of Crohn's disease and modern therapies for inflammatory bowel disease. Dietary and medical treatment of irritable bowel syndrome.

My qualifications & training

My private practice

Information for healthcare professionals (Bupa patients only, last 12 months)

Procedures completed

X3510
IV sedation administered by operator - (5-50)

Spire Norwich Hospital (5-50)
H2002
Diagnostic colonoscopy, includes forceps biopsy of colon and ileum - (5-50)

Spire Norwich Hospital (5-50)
G8082
Diagnostic oesophago-gastro-duodenoscopy (OGD) and immediate colonoscopy includes forceps biopsies, biopsy test and dye spray (as sole procedure) - (5-50)

Spire Norwich Hospital (1-5)
G6500
Diagnostic oesophago-gastro-duodenoscopy (OGD) includes forceps biopsy, biopsy urease test and dye spray - (5-50)
H2003
Therapeutic colonoscopy with snare loop biopsy or excision of lesion - (1-5)

Spire Norwich Hospital (1-5)
H2502
Diagnostic flexible sigmoidoscopy (including forceps biopsy and proctoscopy) - (1-5)

Spire Norwich Hospital (1-5)
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