- Fee assured
- Verified this account
- Lower GI surgery
I was appointed in 2010 as a general and colorectal surgeon. In 2017 I was appointed honorary senior lecturer at the University of Liverpool.
I am experienced in all aspects of general and colorectal surgery with a particular interest in colorectal cancer where I have maintained a 0% 90 day mortality since appointment.
I perform over 200 colonoscopies a year with a completion rate of over 95%.
I am also expert in all other colorectal and general surgical conditions and procedures including inguinal and abdominal wall hernia, haemorrhoids, fissure in ano, fistula in ano and inflammatory bowel disease.
I also run a specialist bowel dysfunction clinic with an interest in pelvic floor failure and IBS.
I have a strong translational and clinical trial research interest in advanced colorectal cancer and run a research team at the Institute of Translational Medicine at Liverpool University. I am the Chief Investigator of the national multi centre study HiP study which and am also involved in a number of other clinical trials as co-investigator and/or data monitoring.
Areas of interest
Colorectal (bowel) cancer; Pelvic floor surgery; Colorectal surgery (lower GI); Incontinence (urine / faeces); Surgery of the gallbladder; Hernia surgery; Haemorrhoids; Anal fistula; Fissures, IBS, Inflammatory Bowel Disease
Current NHS consultant posts held
Consultant General and Colorectal Surgeon
Countess of Chester Foundation Trust
Honorary Senior Lecturer, Institute of Translational Medicine, University of Liverpool
Visiting Professor, Faculty of Health and Social Care, University of Chester
Lead for Colorectal Research, Countess of Chester NHS Trust (2010-present)
Chair of Countess of Chester NHS Trust Research and Development Committee (2013-2016)
Member of NCRI Colorectal subgroup (2014-present)
Member of ACPGBI R&A Committee (2016-present)
R&A Representative on NBOCAP Clinical Advisory Group (2017-present)
Northwest Coast SRG Surgery lead 2017-present
Northwest Coast Network Lead Colorectal Surgery (2016-present)
Chief Investigator for HiP study (UK multicentre, prospective, cohort study)
Lead investigator National Rectal Cancer Biomarker Study
Member of DMC: PREPARE ABC (HTA funded prehabilitation study)
Member of National Research Groups: IMPACT (advanced colorectal cancer) and GI recovery group (ACPGBI/BDRF collaboratives)
Local PI for FoxTroT, HiP, ADD ASPIRIN, CREST2 and HART portfolio trials
Cycling and walking
Art and reading
Bowel Disease Research Foundation (BDRF)
Development of Standardised Rectal Cancer Biopsy 2016/17 £10,000
Bowel Disease Research Foundation
Role of Acid Ceramidase in rectal cancer 2015/16 £12,500
Bowel Disease Research Foundation
HiP study 2016-19 £39,700
BDRF Travelling Fellowship
HiP study 2015 £5,000
Mersey Deanery Madel fellowship
Mechanisms of radiation damage in rectal cancer 2014-16 £80,000
Matthew A et al. Prospective patient stratification into robust cancer-cell intrinsic subtypes from colorectal cancer biopsies . Submitted and under revision J Pathology
Bowden D et al. Predicting Response To Chemoradiotherapy In Rectal Cancer -Proteomic Profiling Reveals Acid Ceramidase As A Potential Novel Biomarker And Therapeutic Target. Accepted pending revision. J Proteomics
Lee SL et al. Primary Colorectal Cells Culture as a Translational Research Model. Methods Mol Biol. 2018;1709:97-105
Sutton PA et al Exome sequencing of synchronously resected primary colorectal tumours and colorectal liver metastases to inform oncosurgical management..Eur J Surg Oncol. 2017 Nov 13. pii: S0748-7983(17)
Grainger J et al. Incidental Mesenteric Paraganglioma: A Case Report and Literature Review., Ann Coloproctol. 2017 Oct;33(5):197-200.
The relationship between method of anastomosis and anastomotic failure after right hemicolectomy and ileo-caecal resection: an international snapshot audit. 2015 European Society of Coloproctology collaborating group. Colorectal Dis. 2017 Mar 6
Lee SL et al.Re-examining HSPC1 inhibitors. Cell Stress Chaperones. 2017 Mar;22(2):293-306
McNair AG et al.ORACLE Collaboration. A national patient and public colorectal research agenda: Integration of consumer perspectives in bowel disease through early consultation. Colorectal Dis. 2016 Nov 21.
Sutton P et al. Evaluation of a tissue stabilisation gel Allprotect to facilitate clinical sampling for translational research in surgical trials. Br J Surg. 2015 Jan, 102:124-32
Simpson GS et al. The aetiology of delay to commencement of adjuvant chemotherapy following colorectal resection. Int J Surg Oncol. 2014
Sheikh AA et al.Outcome of colorectal cancer resection in octogenarians. S Afr J Surg. 2013 May 3;51(2):68-72.
Thornton M et al. Management and outcome of colorectal anastomotic leaks. Int J Colorectal Dis. 2011 Mar;26(3):313-20
Sheikh AA et al. The expression of S100A8 in pancreatic cancer-associated monocytes is associated with the Smad4 status of pancreatic cancer cells. Proteomics. 2007 Jun;7(11):1929-40.
Thompson CC et al.Pancreatic cancer cells overexpress gelsolin family-capping proteins, which contribute to their cell motility. Gut. 2007 Jan;56(1):95-106.
Vimalachandran D et al. High nuclear S100A6 (Calcyclin) is significantly associated with poor survival in pancreatic cancer patients. Cancer Res. 2005 Apr 15;65(8):3218-25.
Since appointment in 2010 I have maintained a 0% 90 day mortality in my major cancer resections and accordingly have maintined a low complication rate.
My annual appraisal confirms that my outcomes in all other domains such as readmission rate, infection rates and colonoscopy rates are also excellent.
I also engage in regular feedback from patients and this has always been very positive.
- Basic Medical Degree MB ChB University of Liverpool 1997
- Doctorate MD University of Liverpool 2006
- Fellow Royal College of Surgeons of England FRCS RCS England 2009
- Post Graduate Certificate in Medical Education University of Chester 2013
Reference number 4409483
Professional bodies (positions held - last 3 yrs)
- Colorectal Subgroup National Cancer Research Institute 2015
- Research and Audit Commitee Association of Coloproctology of Great Britain and Ireland 2016
- North West Coast Lead for Surgery National Institute Health Research (NIHR) 2017
- Secretary Liverpool Northwest Surgical Society 2017
Details of entry to specialist register
- CCT General and Colorectal Surgery, 2009
Affiliations / memberships
Member of the Association of Coloproctology of Great Britain and Ireland
- Nuffield Health The Grosvenor Hospital
- 08:30 - 12:30
- 01244 458327
Post treatment communication
Following treatment of a Bupa member, I will communicate with GPs in line with Department of Health, GMC and appropriate professional bodies guidelines.
In the event of an urgent query following treatment, Bupa members should use the following contact details
Grosvenor Nuffield Chester 01244 680444