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Dr Nick Plowman was a senior scholar at Cambridge University with a Double First in Medical Sciences and Natural Sciences; he returned to Cambridge to write his thesis (macrophages and lung cancer).
On returning to St Bartholomew's Hospital, he specialised in Oncology including research and development. Dr Nick Plowman is now a Senior Oncologist at Barts Health NHS Trust.
During his clinical career, Dr Plowman introduced the first aromatase inhibitor into breast cancer treatment, the most important drug group in breast cancer management for the last 25 years and one which changed best standard for breast cancer.
Meanwhile, in parallel hormonal research, Dr Plowman first noted the adrenosuppressive effect of low dose glucocorticords, and thereby the significant fall in adrenal androgen production, important in androgen deprivation (post-testicular suppression) in prostate cancer. This hormonal research has been a gamechanger in standard care for both breast and prostate cancer respectively.
Dr Plowman's team is currently active in research of androgen signalling and prostate cancer, which also has implications for triple negative breast cancer.
Dr Plowman has been a pioneer in stereotactic radiation therapy "radiosurgery" with 20 serial papers in the British Journal of Neurosurgery on the applications in brain tumours and brain metastases. He is one of Europe's most experienced practitioners of focal radiation oncology (brain and body).
During the last 20 years, Dr Plowman's team have been active in DNA repair research which has major implications for cancer genomics. With his team, he has discovered two new DNA repair fault diseases, with far reaching implications for cancer genomics. His oncology clinic in 20 Harley Street is a leader in cancer genomics and Dr Plowman advises two genomics' companies and has an interest in liquid biopsy (cell free DNA in circulating tumour cells) for screening, diagnosis and diagnosing cancer relapse after first therapy as well as predicting best therapy (by NGS) for cancers during their evolution.
The Oncology Clinic at 20 Harley Street specialises in optimising cancer treatment based on predictive testing and genomic analyses; it co-operates with top specialists in all surgical, medical/clinical oncology, radiology, nuclear medicine and radiotherapy - to deliver the advanced service to cancers patients. Co-operation with advanced genomics companies allow modern predicting testing for the treatment.
Areas of interest
Dr Nick Plowman has a special clinical interest in; breast, brain, endocrine & urological cancers; cancers in children & young persons (chemotherapy & radiotherapy); stereotactic radiotherapy (CyberKnife And GammaKnife).
Current NHS consultant posts held
Barts Health NHS Trust
Breast, brain, endocrine & urological cancers; cancers in children & young persons (chemotherapy & radiotherapy); stereotactic radiotherapy (CyberKnife And GammaKnife).
Cambridge University Double first in Medicine and Natural Sciences.
Senior Scholar at Emmanuel College in 1982.
Roentgen Prize: "New Radiotherapy Techniques" in 1990.
International Union Against Cancer (UICC): Roll of Honour in 1997.
Royal College of Radiologists: Frank Ellis Medal in 1999.
Published around 300 original research papers in clinical oncology.
- Honours, Medicine, 1st Class. Cambridge University 1971
- MA. MD. FRCP. FRCR, Medicine, Honours. Guy’s Hospital. 1974
Reference number 1735534
Affiliations / memberships
MA, MD, FRCP, FRCR